Education
He earned his M.D. and Ph.D. atResearch
His interests are in studying sarcomagenesis, cancer biology and radiation oncology. His highest cited papers are "Conversion of Bcl-2 to a Bax-like death effector by caspases", at 1332 times, and "Restoration of p53 function leads to tumour regression in vivo", at 1320 times, according to Google Scholar.Publications
*Yoon, SW, Cramer, CK, Miles, DA, Reinsvold, MH, Joo, KM, Kirsch, DG, and Oldham, M. "A precision 3D conformal treatment technique in rats: Application to whole-brain radiotherapy with hippocampal avoidance." Medical physics 44, no. 11 (November 2017): 6008–6017. *Dodd, RD, Lee, C-L, Overton, T, Huang, W, Eward, WC, Luo, L, Ma, Y, Ingram, DR, Torres, KE, Cardona, DM, Lazar, AJ, and Kirsch, DG. "NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response." Cancer research 77, no. 16 (August 2017): 4486–4497. *Huang, J, Chen, M, Whitley, MJ, Kuo, H-C, Xu, ES, Walens, A, Mowery, YM, Van Mater, D, Eward, WC, Cardona, DM, Luo, L, Ma, Y, Lopez, OM, Nelson, CE, Robinson-Hamm, JN, Reddy, A, Dave, SS, Gersbach, CA, Dodd, RD, and Kirsch, DG. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nature communications 8 (July 10, 2017): 15999-. *Castle, KD, Chen, M, Wisdom, AJ, and Kirsch, DG. "Genetically engineered mouse models for studying radiation biology." Translational Cancer Research 6, no. S5 (July 2017): S900-S913. *McConnell, AM, Yao, C, Yeckes, AR, Wang, Y, Selvaggio, AS, Tang, J, Kirsch, DG, and Stripp, BR. "p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway." Cell reports 17, no. 9 (November 2016): 2173–2182.References
{{DEFAULTSORT:Kirsch, David Fellows of the American Association for the Advancement of Science Duke University faculty American oncologists Living people Johns Hopkins University alumni Year of birth missing (living people)